Table 4. Comparison of α-glucosidase inhibitory effects of fingerroot
Samples | Inhibition (%)1) | IC50(μg/mL) |
500 μg/mL | 250 μg/mL | 125 μg/mL | 62.5 μg/mL | 31.3 μg/mL |
80% MeOH ext. | 75.7±1.1b | 60.7±2.3b | 44.0±4.1c | 30.4±1.9c | 25.9±2.9c | 151.6±3.1b |
80% EtOH ext. | 70.1±1.4b | 40.6±2.2c | 19.5±2.1d | 13.1±1.8d | 9.0±2.2e | 306.7±2.9a |
80% Acetone ext. | 66.9±2.1b | 41.4±1.4c | 31.0±1.1c | 16.4±2.1d | 9.8±1.2e | 296.3±2.3a |
Hot water ext. | 24.6±1.0c | 19.7±2.1d | 17.5±1.0d | 15.9±2.6d | 11.5±1.9d | >500a |
Acarbose2) | 65.9±1.1b | 49.5±1.8c | 25.4±1.9c | 15.2±1.3d | 8.1±1.1e | 281.9±1.6a |
Inhibitory effects are expressed as the means±SD of triplicate experiments. Different letters (a-e) within the same column indicate significant differences (p<0.05).
Acarbose was used as a positive control.