Table 5. α-Glucosidase inhibition activities of P. chinense Purch seed extracts using different extraction solvent
Extraction solvent | Inhibition activity (%) | IC50 (μg/mL) | Acarbose1) IC50 (μg/mL) |
100 (μg/mL) | 50 (μg/mL) | 25 (μg/mL) | 12.5 (μg/mL) | 6.25 (μg/mL) |
Water | 5.26±0.8c2) | 5.22±1.7b | 4.21±0.2c | 4.05±0.4b | 0.96±2.1a | ND3) | |
75% ethanol | 84.19±0.7a | 60.46±4.1a | 42.75±1.5a | 18.53±3.4a | 10.69±7.3a | 46.47±2.3**4) | 33.77±3.8 |
75% methanol | 59.12±3.1b | 46.80±5.7a | 17.00±3.9b | 8.24±2.6b | 4.79±3.7a | 70.97±2.3 | |
Acarbose was used as a positive control.
Mean±SE (n=3) within each column followed by different letters are significantly different (p<0.05).
ND, not detected.
Mean±SE (n=3) within each column followed by **means p<0.01 by independent t-test.