Table 4. Inhibitory effects of fraction extracts from P. persica twigs and its solvent-soluble portions against α-glucosidase
Samples | Inhibition activity (%) | IC50 values (μg/mL) |
500 μg/mL | 250 μg/mL | 125 μg/mL | 62.5 μg/mL | 31.3 μg/mL |
Hot water | 81.9±0.122)c3) | 81.4±0.17c | 61.0±0.16c | 34.9±0.15c | 19.0±0.14c | 97.0±9.8c |
n-Hexane layer | 24.7±0.16e | 14.8±0.14f | 8.3±0.16f | 4.4±0.17f | 1.0±0.12f | >500 |
EtOAc layer | 99.3±0.17a | 95.2±0.13b | 85.5±0.14a | 64.6±0.18a | 42.7±0.16a | 38.2±1.6e |
n-BuOH layer | 99.1±0.16a | 96.1±0.14a | 84.1±0.13b | 61.3±0.12b | 35.1±0.18b | 47.0±0.8d |
H2O layer | 60.4±0.18d | 44.2±0.12e | 24.6±0.14e | 13.1±0.16e | 10.2±0.16e | 337.5±18.7a |
Acarbose1) | 91.9±0.16b | 70.1±0.16d | 49.5±0.13d | 30.4±0.18d | 16.4±0.14d | 122.2±7.6b |
Acarbose was used as a positive control substance.
Mean±SD (n=3).
a-fValues with different superscript letters in the column are significantly different (p<0.05).