Table 5. Inhibitory properties of fraction extracts from P. persica twigs and its solvent-soluble portions against α-amylase
Samples | Inhibition activity (%) | IC50 values (μg/mL) |
500 μg/mL | 250 μg/mL | 125 μg/mL | 62.5 μg/mL | 31.3 μg/mL |
Hot water | 78.7±0.162)d3) | 62.3±0.15d | 43.6±0.12d | 26.5±0.13d | 9.4±0.15e | 163.9±7.4b |
n-Hexane layer | -4) | - | - | - | - | >500 |
EtOAc layer | 90.2±0.12b | 81.9±0.12b | 59.6±0.15b | 50.3±0.16b | 31.2±0.16b | 69.6±6.1d |
n-BuOH layer | 84.8±0.15c | 74.3±0.16c | 59.2±0.16c | 41.5±0.12c | 26.9±0.13c | 88.8±0.9c |
H2O layer | 71.0±0.13e | 55.9±0.17e | 37.0±0.13e | 18.9±0.14e | 14.5±0.12d | 213.3±11.3a |
Acarbose1) | 99.9±0.18a | 95.8±0.16a | 92.4±0.13a | 62.0±0.12a | 32.6±0.14a | 46.7±2.1e |
Acarbose was used as a positive control substance.
Mean±SD (n=3).
a-eValues with different superscript letters in the column are significantly different (p<0.05).
-, not tested.